Recently, Huang Weimin team of the Chemistry College of Jilin University combined 3D printing technology and electrochemical surface modification technology to develop a new medical titanium alloy composite material . It is understood that this new material has good biocompatibility and can reduce the risk of immune rejection of organisms and reach the international leading level.
Titanium and its alloys were once considered to be the most ideal implantable metals in the body due to their excellent mechanical strength and plasticity. However, traditional titanium and its alloys are difficult to achieve specific implantation in different patients due to production processes and conditions. Therefore, it is easy to cause postoperative effusion, which causes inflammation and infection. In response to the defects of traditional titanium alloys, Huang Weimin's team is coated with a layer of drug-loaded microspheres and cell active materials through electrochemical surface modification technology to make it have good biocompatibility.
At the same time, this new 3D printed titanium alloy material has the advantages of individualization and customization. It can use the computer to simulate the corresponding geometric model according to the test data of different patients, and then output the titanium alloy substrate that fits the patient's wound through the 3D printer, and finally use the electrochemical surface modification technology to modify the surface of the printed titanium alloy. The drug-loaded microspheres and cell active substances are used to ensure the stability of the implant in the patient and achieve the effect of promoting wound healing. At present, Huang Weimin has developed a set of intelligent 3D printing titanium alloy electrochemical modification system around this technology, and has applied for six national invention patents.
The bio-bioassay of this technology has achieved good results. In the future, relying on the Ministry of Science and Technology's 13th Five-Year National Key R&D Program, Huang Weimin's team will further develop new in vivo degradable metal composite materials to avoid the risk of secondary surgery to remove implants, and will be widely used in skull repair, limb repair, Implanted stents and oral plastics and other medical fields. At the same time, the team will expand cooperation with universities, enterprises, hospitals and institutions at home and abroad to form an integrated chain of production, education and research, promote the transformation of scientific research results and actual production applications, and promote innovation and development of the medical industry.
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